Journal Article

·2009

cDNA microarray image analysis

Ersin Tozduman YTU , Songül Albayrak YTU

Abstract

cDNA microarray image analysis has grown very important these days because of the growing field which it's part of: microarray expression analysis. In this work we propose a new cDNA microarray image analysis system. A cDNA microarray analysis system consists of three main parts which are gridding, segmentation and information extraction, respectively. In gridding stage we propose a new automated gridding technique which is based on mathematical morphology. For segmentation we propose two different algorithm which are based on K-Means clustering and Fuzzy C-Means clustering respectively. On the final stage, information extraction, our proposed system uses a classical approach which calculates background values locally. The proposed system has open parts in the way of developement and is still being worked on.

Keywords

Cluster analysis Computer science Complementary DNA Segmentation Image segmentation Mathematical morphology Microarray Artificial intelligence Pattern recognition (psychology) Microarray analysis techniques Gene chip analysis Fuzzy logic Feature extraction Data mining Image (mathematics) Image processing Biology Gene expression Gene

Subject Areas

Gene expression and cancer classification ·Molecular Biology ·Life Sciences
Machine Learning in Bioinformatics ·Molecular Biology ·Life Sciences
Image Retrieval and Classification Techniques ·Computer Vision and Pattern Recognition ·Physical Sciences