Abstract
New 1-[(1,3-thiazol-2-ylamino)methyl]-2-naphthols were obtained by condensation of 2-aminothiazole, aromatic aldehydes, and 2-naphthol in the presence of (+)-camphor-10-sulfonic acid ((+)-CSA) as an effective catalyst under ultrasound-promoted solvent-free conditions. The 1-[(1,3-thiazol-2-ylamino)methyl]-2-naphthol derivatives were converted in ring-closure reaction with formaldehyde to the corresponding naphthoxazine derivatives.
Keywords
Chemistry
Catalysis
Ring (chemistry)
Formaldehyde
Condensation
Sulfonic acid
Camphor
Solvent
Medicinal chemistry
Closure (psychology)
Organic chemistry
Subject Areas
Multicomponent Synthesis of Heterocycles
·Organic Chemistry ·Physical Sciences
Synthesis and biological activity
·Organic Chemistry ·Physical Sciences
Synthesis and Characterization of Heterocyclic Compounds
·Organic Chemistry ·Physical Sciences
Citations by Year
2017: 2
2023: 2
2024: 3
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