Journal Article

·2020

Determination of Cell Stiffness Using Polymer Microbeads as Reference

Sevde Omeroglu , Rahmetullah Varol YTU , Zeynep Karavelioğlu YTU , Aslıhan Karadag , Yasemin Başbınar , Muhammed Enes Oruc YTU , Hüseyin Üvet YTU

2020 Medical Technologies Congress (TIPTEKNO)

Abstract

Knowing the mechanical properties of cells is very important in cell detection, analysis of cell activities, diagnosis and drug treatment. The determination of cell stiffness, which used effectively in cell analysis, is carried out with different measurement techniques. In this study, the stiffness of cells is determined by comparison to the displacement of polystyrene microparticles induced by vibration generated by piezoelectric transducers. The difference of stiffness of the cells and polystyrene microparticles is measured using a digital holographic imaging technique.

Keywords

Materials science Stiffness Polystyrene Biomedical engineering Vibration Polymer Displacement (psychology) Transducer Composite material Cell Acoustics Chemistry

Subject Areas

Microfluidic and Bio-sensing Technologies ·Biomedical Engineering ·Physical Sciences
Cellular Mechanics and Interactions ·Cell Biology ·Life Sciences
Digital Holography and Microscopy ·Atomic and Molecular Physics, and Optics ·Physical Sciences

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