Book Series Article

·2016

Electrospun Poly(ε-Caprolactone)/Bovine Hydroxyapatite (BHA) Composite Nanofibers for Bone Tissue Engineering

M. Kagan Keler YTU , Sibel Dağlilar YTU , Oğuzhan Gündüz YTU

Key engineering materials

Abstract

Tissue engineering applications have opened a different future-promising era for critical injuries, defects and diseases. Bone tissue engineering is the part of tissue engineering which aims to stir up new practical bone re-formation via the interactive combination of biomaterials and cells. Poly (e-caprolactone) (PCL) is a unique semi crystalline polymer material which handles several important features such as biocompatibility, high biomedical durability and degradation properties. Bovine hydroxyapatite (BHA) is another biocompatible material which provides to get ultimate mechanical behavior in composite designs. Because of their high biocompatibility, PCL and BHA were integrated the electrospinning system together. The system was revised for multi-feeding needle equipment. Eight dissimilar tissue scaffolds were produced and investigated for this recent work.

Keywords

Biocompatibility Electrospinning Materials science Tissue engineering Caprolactone Composite number Nanofiber Biocompatible material Bone tissue Biomedical engineering Polyester Polymer Composite material Engineering Polymerization

Subject Areas

Electrospun Nanofibers in Biomedical Applications ·Biomaterials ·Physical Sciences
Bone Tissue Engineering Materials ·Biomedical Engineering ·Physical Sciences

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