Journal Article

·2014

Enhanced Bone Regeneration in Rabbit Tibial Defects İmplanted with Newly Fabricated Bioceramic Bone Grafts

Mehtap Demirel , B. Aksakal YTU

International Journal of Applied Ceramic Technology

Abstract

Hydroxyapatite ( HA )‐based biografts, HBG s, were synthesized by mixing commercial HA with some additives via solgel method. The obtained HBG s were characterized by mechanical tests, X ‐ray diffractometry, XRD , SEM , and FTIR . The fabricated and commercial grafts were filled into drilled zones in N ew Z eland rabbit tibias. The maximum stress was increased up to 332 MP a and the absorbed energy to 26.79 Joule for the yttria‐added sample H50Y10. The histopathology study suggested that better bone generation was obtained in HA ‐based biografts than in control group, and it was shown that the currently fabricated biografts could be used for biomedical applications.

Keywords

Bioceramic Materials science Rabbit (cipher) Biomedical engineering Composite material Medicine Mathematics Statistics

Subject Areas

Bone Tissue Engineering Materials ·Biomedical Engineering ·Physical Sciences
Orthopaedic implants and arthroplasty ·Surgery ·Health Sciences
Dental Implant Techniques and Outcomes ·Oral Surgery ·Health Sciences

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