Journal Article

·2026 OPEN ACCESS

In vitro evaluation of Schiff base-decorated phthalocyanines for photodynamic therapy in PC3 prostate cancer cells

Nagihan Kocaaǧa YTU , Ayşegül Türkkol , Ceren Can Karanlık YTU , Mehmet Bilgin , Ali Erdogmus YTU

Dalton Transactions

Abstract

Schiff base-functionalized phthalocyanines were tested for photodynamic therapy against PC3 cells. Upon light activation, they efficiently produce reactive oxygen species, showing promise as targeted photosensitizers for prostate cancer PDT.

Keywords

Photodynamic therapy Phthalocyanine Schiff base In vitro Prostate cancer Metal Chemistry Cancer research

Subject Areas

Photodynamic Therapy Research Studies ·Pulmonary and Respiratory Medicine ·Health Sciences
Porphyrin and Phthalocyanine Chemistry ·Materials Chemistry ·Physical Sciences
Nanoplatforms for cancer theranostics ·Biomedical Engineering ·Physical Sciences