Abstract
Water-soluble binary and ternary copper complexes of polyelectrolytes were synthesized, and the toxicity of these complexes was tested in mouse fibroblast cell line (L929) in vitro. Both the binary and ternary complexes were prepared at the ratio of 0.4 mole copper(II) ions per monomer of acrylic acid and 0.5 mole copper(II) ions per monomer of methyl vinyl ether maleic anhydride, furthermore at the ratio of 1 and 2 mole bovine serum albumin per mole of polyacrylic acid and poly(methyl vinyl ether-co-maleic anhydride), respectively. Compared to binary copper(II)-polyelectrolyte complexes, these ternary complexes have been determined to be of least toxicity.
Keywords
Polyelectrolyte
Maleic anhydride
Ternary operation
Chemistry
Maleic acid
Monomer
Polymer chemistry
Acrylic acid
Copper
Nuclear chemistry
Metal ions in aqueous solution
Polyacrylic acid
Metal
Organic chemistry
Polymer
Copolymer
Subject Areas
Polymer Surface Interaction Studies
·Surfaces, Coatings and Films ·Physical Sciences
Dendrimers and Hyperbranched Polymers
·Polymers and Plastics ·Physical Sciences
Protein Interaction Studies and Fluorescence Analysis
·Molecular Biology ·Life Sciences
Citations by Year
2014: 1
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