Abstract
. Importantly, the biocompatibility of compound 2 was confirmed in L929 fibroblast cells. While it exhibited concentration-dependent cytotoxicity in the dark, under light irradiation, cell viability remained close to or above the thresholds defined by ISO 10993-5 for non-cytotoxicity. As a result, compound 2 is a multifunctional phthalocyanine derivative that combines diverse biological activities with a safety profile, supporting its potential as a promising candidate for biomedical applications.
Keywords
Singlet oxygen
Antimicrobial
Biocompatibility
Phthalocyanine
Cytotoxicity
Carboxylic acid
Antioxidant
Lipophilicity
Photosensitizer
Chemistry
Photochemistry
Subject Areas
Porphyrin and Phthalocyanine Chemistry
·Materials Chemistry ·Physical Sciences
Photodynamic Therapy Research Studies
·Pulmonary and Respiratory Medicine ·Health Sciences
Porphyrin Metabolism and Disorders
·Molecular Biology ·Life Sciences
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