Journal Article

·2025

Anti-cancer efficacy of novel lonidamine derivatives: Design, synthesis, in vitro, in vivo, and computational studies targeting hexokinase-2

Özgecan Şavluğ İpek YTU , Bilgesu Onur Sucu YTU , Saba Selvi , Fulya Üstün Alkan , Büşra Tiryaki , Hilmi Alkan , Ehsan Sayyah , İlayda Tolu , Mustafa Güzel , Serdar Durdağı ,

European Journal of Medicinal Chemistry

No open-access abstract is available for this article. Use the DOI link on the right to read the full text.

Keywords

Chemistry In vivo In vitro Hexokinase Pharmacology Combinatorial chemistry Biochemistry Stereochemistry Glycolysis Enzyme Biotechnology

Subject Areas

Cancer, Hypoxia, and Metabolism ·Cancer Research ·Life Sciences
Biochemical and Molecular Research ·Molecular Biology ·Life Sciences
Amino Acid Enzymes and Metabolism ·Biochemistry ·Life Sciences

Citations by Year

OpenAlex SDG Match

SDGs auto-classified by OpenAlex (score ≥ 0.4 shown).

Good health and well-being 44%