Journal Article

·2022

Optimisation of liquorice extract microencapsulation and bioaccessibility of its bioactives

Fahriye Şeyma Özcan , Nihat Ali Özcan , Kübra Özkan YTU , Osman Sağdıç YTU

Acta Alimentaria

Abstract

Abstract In this work, functional liquorice powder beverage (FLPB) with standardised glycyrrhizin (GL), glycyrrhetinic acid (GA), carbenoxolone (CBX), and liquiritin (LQ) contents, was produced by encapsulating Glycyrrhiza glabra extract with maltodextrin (MD) by spray drying. Encapsulation parameters of the FLPB were optimised as MD:GL 3.4:1, inlet temperature: 149 °C, and air flow: 8.9 L min −1 . GL, GA, LQ, CBX, and yield in powdered beverage produced using these optimised parameters were 6.8 g L −1 , 81.1 mg L −1 , 24.7 mg L −1 , 0.79 g L −1 , and 30.95%, respectively. Moreover, the effect of the encapsulation on the bioaccessibility of GL, GA, CBX, and LQ bioactives in G. glabra was evaluated. According to the obtained results, FLPB exhibited a higher bioaccessibility index for GL, GA, CBX, and LQ compared to the aqueous extract.

Keywords

Chemistry Glycyrrhiza Liquiritin Spray drying Glycyrrhizin Maltodextrin Gum acacia Food science Carbenoxolone Angle of repose Chromatography Nuclear chemistry Materials science Biochemistry High-performance liquid chromatography Pharmacology

Subject Areas

Pharmacological Effects of Natural Compounds ·Pharmacology ·Life Sciences
Phytochemistry and Bioactivity Studies ·Pharmacology ·Life Sciences
Silymarin and Mushroom Poisoning ·Pulmonary and Respiratory Medicine ·Health Sciences