Journal Article

·2019

Rapid, Accurate and Sensitive Determination of Fenpropathrin as Insecticide in Dried Strawberry Samples by High Performance Liquid Chromatography, and In Vivo Stability and Behavior under Gastric Conditions

Zeynep Tekin YTU , Buse Tuğba Zaman YTU , Sezgin Bakırdere YTU

Chemistry Letters

Abstract

An analytical method was validated for the determination of fenpropathrin in dried strawberry samples using RP-HPLC. Under the optimal conditions, LOD was obtained as 3.2 µg L−1. The method demonstrated good linearity (R2 > 0.9997) and satisfactory repeatability (%RSD ≤ 4.12) at low concentrations. The validated assay was applied to spiked samples. High percent recovery values were obtained. The analyte was subjected to simulated gastric conditions, and no major change of the analyte peak areas and retention time throughout 300 min was observed. This graphical abstract represents the developed HPLC-UV method. The samples were ground into powdery form prior to taking 0.10 g for extraction with 10 mL of methanol. The samples were then mixed on a mechanical shaker for 45 min and centrifuged for 2.0 min. The supernatant was filtered through a 0.45 µm syringe filter, diluted and analyzed under the optimum parameters.

Keywords

Chemistry Chromatography Repeatability Analyte High-performance liquid chromatography Extraction (chemistry) Filter paper Methanol

Subject Areas

Pesticide Residue Analysis and Safety ·Food Science ·Life Sciences
Insect and Pesticide Research ·Insect Science ·Life Sciences
Pesticide and Herbicide Environmental Studies ·Pollution ·Physical Sciences

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