Abstract
Abstract The use of partial least-squares spectrophotometric calibration for the simultaneous determination of suppositories in a multicomponent formulation is presented. This method is applied to the deternination of acetaminophen and phenobarbital in suppository preparations. The results show that these components in a molar ratio of about 61:1 in suppositories have been determined simultaneously with high precision.
Keywords
Suppository
Chemistry
Chromatography
Partial least squares regression
Phenobarbital
Calibration
Acetaminophen
Calibration curve
Spectrophotometry
Pharmacology
Detection limit
Statistics
Mathematics
Biochemistry
Subject Areas
Analytical Methods in Pharmaceuticals
·Analytical Chemistry ·Physical Sciences
Analytical Chemistry and Chromatography
·Spectroscopy ·Physical Sciences
Pesticide Residue Analysis and Safety
·Food Science ·Life Sciences
Citations by Year
2016: 1
2022: 1
2023: 1
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